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硅纳米结构的设计及其在生物成像、分析检测、生物应用的研究工作,作为J. Am. Chem. Soc.、Angew. Chem. Int. Ed. Appl. Phys. Lett.以及Advanced Materials等封面文章报道。(2009-今)

2009年课题组成立以来的几篇代表性工作:

1.课题组一年级博士生钟旖菱同学近期关于硅纳米生物探针的设计及其生物成像的工作,由于其在相关领域的重要性,被国际权威期刊J. Am. Chem. Soc.作为封面文章发表,并作为JACS spotlights专题报道。

Yiling Zhong, Fei Peng, Feng Bao, Siyi Wang, Xiaoyuan Ji, Liu Yang, Yuanyuan Su, Shuit-Tong Lee*, and Yao He*. " Large-Scale Aqueous Synthesis of Fluorescent and Biocompatible Silicon Nanoparticles and Their Use as Highly Photostable Biological Probes" J. Am. Chem. Soc., 2013, 135 (22), pp 8350–8356 (IF:9.907)

 

2.硅基纳米结构用于致癌基因高灵敏多元分析检测的工作,作为开创性的研究(ground-breaking research)工作被Appl. Phys. Lett.创刊50周年特刊收录(左),并被国家自然科学基金委官方网站专题报道(右)。

Ziyun Jiang, Xiangxu Jiang, Shao Su, Xinpan Wei, Shuit-Tong Lee, Yao He*. "Silicon-based reproducible and active surface-enhanced Raman scattering substrates for sensitive, specific, and multiplex DNA detection" Appl. Phys. Lett. 2012, 100, 203104 (IF=3.844, Cited times=5) (Cover, selected for the May 28, 2012 issue of Virtual Journal of Nanoscale Science & Technology, APL’s 50th Anniversary Collection Editor’s picks as one of the ground-breaking research (left),highlighted by NSFC official website(right))

 

3.多色荧光纳米材料(修饰有量子点的硅线)用于细胞成像,该工作作为底封面发表在Angew. Chem. Int. Ed.(2011),并被Nature Asia Materials作为亮点报道,同时被选为very important paper (VIP)

Yao He*, Yiling Zhong, Fei Peng, Xinpan Wei, Yuanyuan Su, Shao Su, Wei Gu, Liangsheng Liao, Shuit-Tong Lee*. "Highly luminescent water-dispersible silicon nanowires for long-term immunofluorescent cellular imaging" Angew. Chem. Int. Ed. 2011, 123, 3136-3139 (IF=13.455, Cited times=8) (Back Cover, recommended the very important paper (VIP), highlighted by Nature Asia Materials)

 

4.我组发表在2011年Biomaterials的一篇文章"In vivo distribution, pharmacokinetics, and toxicity of aqueous synthesized cadmium-containing quantum dots"被Nanomedicine作为亮点报道,并表示这是纳米生物学领域的一大重大科学进展

Yuanyuan Su, Fei Peng, Ziyun Jiang, Yiling Zhong, Yimei Lu, Xiangxu Jiang, Qing Huang, Chunhai Fan*, Shuit-Tong Lee*, Yao He*. "In vivo distribution, pharmacokinetics, and toxicity of aqueous synthesized cadmium-containing quantum dots" Biomaterials 2011, 32, 5855-5862 (IF=7.404, Cited times=20) (Highlighted by Nanomedicine as "the most importance events and research in the field of nanomedicine". Nanomedicine 2011, 5, 765.)

 

5.我组发表在2010年nano today的一篇综述文章 "Silicon nanostructures for bioapplications" 被Science Direct评为该杂志the 25 hottest papers in the journal,排名第四

Yao He*, Chun-Hai Fan, Shuit-Tong Lee*. "Silicon nanostructures for bioapplications" Nano Today 2010, 5, 282-295. (IF=15.355, Cited times=36) (invited review, ranked the 4th in the 25 hottest papers in the journal on Science Direct)

 

6.硅纳米微球作为一种新型生物荧光探针用于细胞、蛋白质及DNA检测,该工作作为内封面文章发表在Angew. Chem. Int. Ed.(2009),并被Nature Asia Materials作为亮点报道

Yao He, Zhen-Hui Kang, Quan-Song Li, Chi Him A. Tsang, Chun-Hai Fan*, Shuit-Tong Lee*. "Ultrastable, Highly Fluorescent, and Water-Dispersed Silicon-Based Nanospheres as Cellular Probes" Angew. Chem. Int. Ed. 2009, 121,134-138.(IF=13.455, Cited times=50) (Inside Cover, highlighted by Nature Asia Materials)

7何耀教授、苏媛媛副教授应国际权威出版社Springer(全球第一大科技图书出版公司)的邀请,出版发行国际上第一本系统介绍硅纳米生物技术在生物成像、分析检测和癌症检测与治疗方面的英文专著。

 
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