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课题组宋崇喜、钟旖菱博士等在Analytical chemistry发表论文

发布日期:2015-06-05


题目: Peptide-Conjugated Fluorescent Silicon Nanoparticles Enabling Simultaneous   Tracking and Specific Destruction of Cancer Cells

作者:

Chongxi Song, Yiling Zhong(共同第一作者), Xiangxu Jiang, Fei Peng, Yimei Lu, Xiaoyuan Ji, Yuanyuan Su, and Yao He

单位:
Institute of Functional Nano & Soft Materials (FUNSOM) and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China

摘要:We herein introduce a kind of fluorescent silicon nanoparticles (SiNPs) bioprobes, i.e., peptides-conjugated SiNPs, which simultaneously feature small sizes (<10 nm), biological functionality, stable and strong fluorescence (photoluminescent quantum yield (PLQY): ~28%), as well as favourable biocompatibility. Taking advantages of these merits, we further demonstrate such resultant SiNPs bioprobes are superbly suitable for real-time immunofluorescence imaging of cancer cells. Meanwhile, malignant tumor cells could be specifically destroyed by the peptides-conjugated SiNPs, suggesting potential promise of simultaneous detection and treatment of cancer cells.


影响因子:5.825

分区情况: 2区

链接http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b00853


 
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