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课题组史宇、王后禹博士等在Analytical chemistry上发表论文

发布日期:2016-03-07


题目:Ultrasensitive, Specific, Recyclable, and Reproducible Detection of Lead Ions in Real Systems through a Polyadenine-Assisted, Surface-Enhanced, Raman Scattering Silicon Chip

作者:
Yu Shi, Houyu Wang(共同第一作者), Xiangxu Jiang, Bin Sun, Bin Song, Yuanyuan Su, and Yao He*

单位:
Institute of Functional Nano and Soft Materials (FUNSOM) and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China

摘要:

It is of great significance to accurately and reliably detect trace lead(II) (Pb2+) ions, preferably at sub-nM level due to the possible long-term accumulation of Pb2+ in the human body, which may cause serious threats to human health. However, a suitable Pb2+ sensor meeting the demands is still scanty. Herein, we develop a polyadenine-assisted, surface-enhanced Raman scattering (SERS) silicon chip (0.5 cm × 0.5 cm) composed of core (Ag)-satellite (Au) nanoparticles (Ag−Au NPs)-decorated silicon wafers (Ag−Au NPs@Si) for high- performance Pb2+ detection. Typically, strong SERS signals could be measured when DNAzyme conjugated on the SERS silicon chip is specifically activated by Pb2+, cleaving the substrate strand into two free DNA strands. A good linearity exists between the normalized Raman intensities and the logarithmic concentrations of Pb2+ ranging from 10 pM to 1 μM with a good correlation coefficient, R2 of 0.997. Remarkably, Pb2+ ions with a low concentration of 8.9 × 10−12 M can be readily determined via the SERS silicon chip ascribed to its superior SERS enhancement, much lower than those (∼nM) reported by other SERS sensors. Additionally, the developed chip features good selectivity and recyclability (e.g., ∼11.1% loss of Raman intensity after three cycles). More importantly, the as-prepared chip can be used for accurate and reliable determination of unknown Pb2+ ions in real systems including lake water, tap water and industrial wastewater, with the RSD value less than 12%.



影响因子:5.636

分区情况: 2区

链接http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b04551


 
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