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课题组解娟同学在Nanoscale上发表论文

发布日期:2014-06-19


题目:  Stem-loop DNA-assisted silicon nanowires-based biochemical sensors with ultra-high sensitivity, specificity, and multiplexing capability


作者:Juan Xie, Xiangxu Jiang, Yiling Zhong, Yimei Lu, Siyi Wang, Xinpan Wei, Yuanyuan Su
and Yao He*


单位:
Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China. E-mail: yaohe@suda.edu.cn; Fax: +86-512-65880946




摘要:A class of stem-loop DNA-assisted silicon nanowires (SiNWs)-based fluorescent biosensor is presented in this report. Significantly, the sensor enables rapid and sensitive detection of DNA targets with a concentration as low as 1 pM. Moreover, the large planar surface of SiNWs facilitates simultaneous assembly with different DNA strands, which is favorable for multiplexed DNA detection. On the other hand, the SiNWs-based sensor is highly efficacious for detecting heavy metal ions. Mercury ions (Hg2+) of low concentrations (e.g., 5 pM) are readily identified from its mixture with over 10 kinds of interfering metal ions, even in real water samples. Given that SiNWs can be fabricated in a facile, reproducible and low-cost manner, this kind of SiNWs-based high-performance sensor is expected to be a practical analytical tool for a variety of biological and environment-protection applications.


影响因子:6.233


分区情况: 1区

相关链接:
http://pubs.rsc.org/en/Content/ArticleLanding/2014/NR/C4NR01097C#!divAbstract

 
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