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课题组朱瀛、姜享旭、王后禹博士等在Analytical chemistry上发表论文

发布日期:2015-06-05


题目: A Poly Adenine-Mediated Assembly Strategy for Designing Surface-Enhanced Resonance Raman Scattering Substrates in Controllable Manners

作者:
Ying Zhu, Xiangxu Jiang(共同第一作者), Houyu Wang(共同第一作者),Hui Wan, Bin Sun, Yuanyuan Su, and Yao He

单位:
Institute of Functional Nano & Soft Materials (FUNSOM) and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China

摘要:

In this article, we introduce a Poly Adenine (A)-assisted fabrication method for rationally designing surfaceenhanced resonance Raman scattering (SERRS) substrates in controllable and reliable manners, enabling construction of coresatellite SERRS assemblies in both aqueous and solid phase (e.g., symmetric core (Au)-satellite (Au) nanoassemblies (Au-Au NPs),  and asymmetric Ag-Au NPs-decorated silicon wafers (Ag-Au NPs@Si)). Of particular significance, assembly density is able to be controlled through varying the length of Poly A block (e.g., 10, 30 and 50 consecutive adenines at the 5’ end of DNA sequence,  Poly A10/A30/A50), producing the asymmetric core-satellite nanoassemblies with adjustable surface density of Au NPs assembly on core NPs surface. Based on quantitative interrogation of the relationship between SERRS performance and assemble density, the Ag-Au NPs@Si featuring the strongest SERRS enhancement factor (EF: ~107) and excellent reproducibility can be achieved in optimum conditions. We further employ the resultant Ag-Au NPs@Si as high-performance SERRS sensing platform for selective and sensitive detection of mercury ions (Hg2+) in a real system, with a low detection limit of 100 fM, which is ~5 orders of magnitude lower than the U.S. EPA defined limit (10 nM) in drinkable water. These results suggest the Poly A-mediated assembly method as new and powerful tools for designing high-performance SERRS substrates with controllable structures, facilitating improvement of sensitivity, reliability, and reproducibility of SERRS signals.



影响因子:5.825

分区情况: 2区

链接http://pubs.acs.org/doi/abs/10.1021/acs.analchem.5b00676


 
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