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Cover Paper published in Appl. Phys. Lett. by Ziyun Jiang et al.

Date released: 2012-05-15


Title: Silicon-based reproducible and active surface-enhanced Raman scattering substrates for sensitive, specific, and multiplex DNA detection


Authors: Z. Y. Jiang,1 X. X. Jiang,1 S. Su,1 X. P. Wei,1 S. T. Lee,2 and Y. He1,a)


Departments:
1 Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China
2 Center of Super-Diamond and Advanced Films (COSDAF), City University of Hong Kong, Hong Kong SAR, China and Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China


Abstract: Silicon-based active and reproducible surface-enhanced Raman scattering (SERS) substrate, i.e., silver nanoparticles decorated-silicon wafers (AgNPs@Si), is employed for constructing high-performance sensors. Significantly, the AgNPs@Si, facilely prepared via in situ AgNPs growth on silicon wafers, features excellent SERS reproducibility and high enhancement factor. Our experiment further demonstrates such resultant silicon-based SERS substrate is efficacious for multiplex, sensitive, and specific DNA detection. In particular, single-base mismatched DNA with low concentrations is readily discriminated by using the AgNPs@Si. Moreover, the silicon-based sensor exhibits adequate multiplexing capacity, enabling unambiguous identification of the dual-target DNA detection.


IF: 3.841


 
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